An annual herbaceous plant, black seed (Nigella sativa) is believed to be indigenous to the Mediterranean region but has been cultivated into other parts of the world including Saudi Arabia, northern Africa and parts of Asia.

Tiny and hairy, being no more than 3mm in length, black seed originates from the common fennel flower plant (Nigella sativa) of the buttercup (Ranunculaceae) family. Nigella sativa is sometimes mistakenly confused with the fennel herb plant .
The plant has finely divided foliage and pale bluish purple or white flowers. The flowers grow terminally on its branches while the leaves grow opposite each other in pairs, on either side of the stem. Its lower leaves are small and petiole, and the upper leaves are long (6-10cm). The stalk of the plant reaches a height of twelve to eighteen inches as its fruit, the black seed, matures.

Nigella sativa reproduces with itself and forms a fruit capsule which consists of many white trigonal seeds. Once the fruit capsule has matured, it opens up and the seeds contained within are exposed to the air, becoming black in color (black seeds).

Nigella sativa and its black seed are known by other names, varying between places. Some call it black caraway, others call it black cumin (Kalonji), or even coriander seeds. In English, the Nigella sativa plant is commonly referred to as "Love in a Mist". Nevertheless, this is Nigella sativa, which has been known and used from ancient times and is also known in Persian as Shonaiz.

The most pertinent point to be made about black seed is that it should be regarded as part of an overall holistic approach to health and ideally should be incorporated into one's everyday lifestyle. In this way, the many nutritional and healing properties contained in the seed can help build the body's immune system over time, supplying it with the optimum resources it needs to help prevent and fight illness.

Monosaccharides (single molecule sugars) in the form of glucose, rhamnose, xylose, and arabinose are found in the black seed.
The black seed contains a non-starch polysaccharide component which is a useful source of dietary fiber.

It is rich in fatty acids, particularly the unsaturated and essential fatty acids (Linoleic and Linoleic acid). Essential fatty acids cannot be manufactured by the body alone, and therefore we acquire these from food.
Fifteen amino acids make up the protein content of the black seed, including eight of the nine essential amino acids. Essential amino acids cannot be synthesized within our body in sufficient quantities and are thus required from our diet.
Black seed contains Arginine which is essential for infant growth.
Chemical analysis has further revealed that the black seed contains carotene, which is converted by the liver into vitamin A, the vitamin known for its anti-cancer activity.
The black seed is also a source of calcium, iron, sodium, and potassium. Required only in small amounts by the body, these elements' main function is to act as essential cofactors in various enzyme functions.
A study of black seed's potential anti-tumor principles by the Amala Research Center in Amala Nagar, Kerala (India) in 1991 lent further impetus to Dr. Chakravarty's suggestion for the possible use of black seed in the treatment of cancer.
Using an active principle of fatty acids derived from black seed, studies with Swiss albino mice showed that this active principle could completely inhibit the development of a common type of cancer cells called Ehrlich ascites carcinoma (EAC). A second common type of cancer cells, Dalton's lymphoma ascites (DLA) cells were also used.
Mice which had received the EAC cells and black seed remained normal without any tumor formation, illustrating that the active principle was 100% effective in preventing EAC tumor development.
Results in mice who received DLA cells and black seed showed that the active principle had inhibited tumor development by 50% less compared to mice not given the active principle.
The study concluded, "It is evident that the active principle isolated from nigella sativa seeds is a potent anti-tumor agent, and the constituent long chain fatty acid may be the main active component."
The oil proved to be more effective against many strains of bacteria, including those known to be highly resistant to drugs: V. cholera, E. coli (a common infectious agent found in undercooked meats), and all strains of Shigella spp., except Shigella dysentriae. Most strains of Shigella have been shown to rapidly become resistant to commonly used antibiotics and chemotheraputic agents.